Patients

You need Java to see this applet.

H ome Specialties Experience Physicians Patients Careers
Registration Sponsors Contact Us Location

" Welcome to Juno Research Patient Resources page".

On this page you will find valuable information regarding the process of drug

development,

the importance that volunteer patients play on this process some of the benefits that a

volunteer receives for participating in clinical trials and the opportunity to apply for any

current or upcoming clinical trials.

THE PROCESS OF DRUG DEVELOPMENT

The process of drug development consists of five main phases:

The pre-clinical phase, phase I, Phase II, Phase III, and phase IV.Pre-clinical

Phase:

This is the stage in which extensive laboratory research is conducted and the product or

compound extensively tested in animals and human cells. This is a complicated process that

takes several years of study and experimentation. Before any drug is used in humans, the

pharmaceutical companies have to submit an application to the Food and Drug Administration

(FDA), for evaluation and permission to begin testing in humans. The FDA then evaluates all

the data collected and submitted by the pharmaceutical company and determines if the new-

drug benefits outweigh the risks. Based on the results of this evaluation, they either grant or

denied the petition to start human testing.

Phase One ( I ) :

This phase mainly assess the safety of the new drug and investigates its

side effects. It is the first time that the drug is tested in human subjects. It could last from a

few weeks to several months. It is intended to determine what happens to the drug in the

human body, how it is absorbed, metabolized, and excreted. This initial phase of human

testing involves a limited number of healthy volunteers that usually ranges from 20 to 200
patients

Phase Two ( II ) :

After it has been determined that the drug is safe, it is tested for efficacy

on phase II trials. These trials may last from several months to a few years and involve several

hundred volunteer patients that match specific criteria. Patients participating in phase II clinical

studies are usually randomized to different treatments or arms. These arm treatments include

the investigational drug, placebo or inactive drug, and other already-FDA-approved drugs to

compare the effectiveness of the new drug. These studies are often “blinded”,meaning that

neither the patients nor the research personnel will know to which arm treatment the patient

have been assigned to.

Phase Three ( III ) :

Phase III clinical studies usually involves several thousand patients.

These trials usually last from one to five years and are intended to further all knowledge of

drug safety, effectiveness, side effects, and benefits in large scale populations. These trials

use “randomized” and “blinded” parameters. After the trial is over and all information collected

and analyzed, the pharmaceutical companies can then request approval from the FDA to

market

the drug.

Phase Four ( IV ) :

Phase IV studies are post-marketing studies. In most cases the drug has

already been approved by the FDA and is available in most pharmacies. These trials may last

several months and usually involve thousands of volunteers. They are used to further all

knowledge of the drug, compare it to other drugs, and assess its long-term impact in the

patient’s quality of life.

VOLUNTEERS ROLL

Patients volunteer all over the world to participate in clinical trials. They play a vital roll in the

process of drug development, they are the real heroes of the process, they are the ones that

make the difference and take that extra-step to go forward. All the medications that we find so

readily today in the market are there thanks to millions of volunteers that successfully

completed

clinical trials to better the world of other people. Other people that like them, were

suffering

from conditions that were taking a toll in their quality of life.

VOLUNTEERS BENEFITS

There are many benefits that volunteers receive while participating in a clinical study. Patients

participating in clinical studies receive all study-related doctor visits, laboratory evaluations

and

study medications at no charge for them. The Investigators are constantly checking on

their

condition and evaluating if the study is right for them, providing them with first class

medical

care, and most clinical studies offer monetary compensation for time and travel.

Another benefit

a volunteer receives from participating in a clinical study is the knowledge

that their participation today may save and/or increase the quality of life of countless people
in the future, including those close to them.

PARTICIPATING IN A CLINICAL STUDY

Numerous clinical trials are developed each year. Juno Research is constantly looking and

enrolling patients with the following conditions: Diabetes, High Cholesterol, High Blood

Pressure, Asthma, Allergies, Acute and Chronic Bronchitis, Arthritis, Sexual Dysfunction,

Hepatitis, Urinary Incontinency, Overactive Bladder, Insomnia, Depression,Overweight, Lower

Back Pain, Migraines, Angina, Peripheral Vascular Disease, GERD, Thyroid Problems, Chronic

Anemia, etc.

If you have any of these or other conditions and wish to participate in a clinical study, please

Phone: (713) 779-5494

Or email us at

Patients@junoresearch.us

A courteous representative will answer any questions you might have and offer more

information about currently enrolling clinical trials.

Juno Research,L.L.C

Delivering High Quality Results

Patients